How does Xiapex work?

Xiapex contains collagenase clostridium histolyticum (CCH), which is produced by fermentation of the bacterium clostridium histolyticum. CCH is a proteinase that hydrolyses the triple-helix of collagen under physiological conditions, and therefore can be effective in lysing the collagen deposits seen in Peyronie’s disease. Xiapex acts locally and does not require systemic exposure.30-32

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Dupuytren’s disease

Peyronie’s disease