Non-surgical options

Collagenase clostridium histolyticum is a non-surgical approach in which enzymes (called collagenases) are injected directly into the cord. These enzymes dissolve the collagen to break down the cord. The injection is followed by a procedure the next day during which the finger is extended by the doctor, breaking the cord. In some cases, the cord breaks on its own so the extension procedure is not needed. This treatment does not require the patient to stay in hospital. Anaesthetic is not needed for the injection, although local anaesthetic may be used for the extension procedure.1

Another non-surgical treatment option is percutaneous needle fasciotomy, a technique which uses a needle to cut the cord. The needle is inserted into the palm or fingers to cut (section) the tissues in the palm. The Dupuytren’s cord is sectioned by moving the needle in a sawing motion. This movement is repeated several times. The aim is to break the cord so the finger can be straightened. This technique can be carried out under local anaesthetic and may be performed in a day surgery or doctor’s office without any need for a hospital stay.23

Radiation therapy a further treatment which is usually used for patients who are in the early stages of the disease. The goal is to prevent, or at least delay, the need for surgery. The affected hand is placed under an x-ray or electron beam machine and then radiation is applied to the lumps in the palm. This is repeated over several consecutive days.24

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Dupuytren’s disease

Peyronie’s disease