Durability of response to Xiapex demonstrated in Phase III clinical trails<sup>1</sup>

The long-term extension trial (CORDLESS) is a prospective 5 year trial examining the recurrence and long-term safety with annual interim analyses.

Recurrence was defines as:

  • Contracture increased by ≥ 20o with palpable cord OR
  • Medical/surgical intervention performed (i.e. if surgery/reinjection later performed)
The rate of increase of recurrence appears to have slowed over time1

No new safety signals were identified among subjects who were followed for 5 years after their initial injection of Xiapex.

Are you a healthcare professional?

Dupuytren’s disease

Peyronie’s disease